Related Experiment Video
Updated: Apr 25, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Tracheal stenosis caused by unnoticed foreign bodies
Yuya Ogawara1, Tomoyasu Tachibana, Yorihisa Orita
1Department of Otolaryngology, Himeji Red Cross Hospital, Himeji, Hyogo 670-8540, Japan.
This study reports a rare case of tracheal stenosis caused by microscopic foreign bodies, likely linked to repeated tracheal intubations. Treatment involved laser photoresection, resulting in a good patient outcome.
Area of Science:
- Pulmonology
- Otolaryngology
- Pathology
Background:
- Tracheal stenosis is a serious condition that can compromise airway patency.
- Microscopic foreign bodies are an unusual cause of tracheal stenosis.
- Intratracheal intubation is a common medical procedure with potential complications.
Purpose of the Study:
- To report an extremely rare case of tracheal stenosis caused by unnoticed microscopic fiber-like foreign bodies.
- To investigate the potential link between intratracheal intubations and the development of this condition.
- To describe the diagnostic and therapeutic approach.
Main Methods:
- A 66-year-old woman presented with dyspnea and inspiratory stridor.
- Diagnostic tools included magnifying electroendoscopy and computed tomography.
- Tracheotomy and biopsy were performed for histological examination.
- Treatment involved semiconductor laser photoresection.
Main Results:
- Magnifying electroendoscopy and CT revealed circumferential tracheal stenosis.
- Histological examination showed chronic inflammation and deposition of fiber-like foreign bodies.
- The patient had a history of four intratracheal intubations.
- Laser photoresection resulted in a good postoperative course.
Conclusions:
- This case represents the first report in English literature of tracheal stenosis caused by unnoticed foreign bodies.
- The fiber-like foreign bodies may be related to chronic inflammation secondary to repeated intratracheal intubations.
- Early diagnosis and appropriate intervention are crucial for managing such rare conditions.
Related Concept Videos
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Pulmonary Cycle: Exhalation

