Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.2K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.2K
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

1.7K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thromboembolic disease in testicular germ cell tumors-real-world evidence of three Portuguese institutions.

Frontiers in oncology·2026
Same author

Screening for Cardiac Amyloidosis When Conducting Carpal Tunnel Surgery.

Journal of clinical medicine·2025
Same author

Clinical Management of Euglycemic Ketoacidosis in a Cat With Congenital Diabetes Mellitus Treated With Insulin and Dapagliflozin.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2025
Same author

[Intercontinental Multidisciplinary Oncology Videoconferencing between the South Pacific and the French mainland: Reasons for medical evacuation after more than 2000 cases of cancers discussed].

Bulletin du cancer·2025
Same author

Real-Life Experience of HER2 (Human Epidermal Growth Factor Receptor 2)-Positive Advanced Breast Cancer Patients Treated With T-DXd (Trastuzumab Deruxtecan): A Multicentric Portuguese Study.

Cureus·2025
Same author

[Clinical research in oncology in French Overseas Territories: Challenges, strengths, and available resources].

Bulletin du cancer·2025
Same journal

Canaliculitis associated with multiple retained silicone punctal plugs and concurrent biodegradable plug placement.

BMJ case reports·2026
Same journal

Bilateral vocal cord paralysis in multifocal motor neuropathy.

BMJ case reports·2026
Same journal

Multiple visceral artery aneurysms and type II Abernethy malformation in a patient with autoimmune hepatitis.

BMJ case reports·2026
Same journal

Congenital nasolacrimal duct cyst complicating as an orbital abscess.

BMJ case reports·2026
Same journal

Management of <i>Achromobacter xylosoxidans</i> bacteraemia with an atypical antimicrobial resistance pattern.

BMJ case reports·2026
Same journal

Unintentional chronic acetaminophen overuse as an under-recognised cause of liver injury.

BMJ case reports·2026
See all related articles

Related Experiment Video

Updated: Apr 25, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

3.1K

Paratesticular sarcomas: two cases with different evolutions.

Margarida Matias1, Miguel Carvalho2, Luisa Xavier1

  • 1Department of Medical Oncology, Hospital Garcia de Orta, Almada, Portugal.

BMJ Case Reports
|August 23, 2014
PubMed
Summary
This summary is machine-generated.

Paratesticular sarcomas are rare cancers. These case reports highlight varied recurrence patterns, with one case showing metastasis 30 years after initial treatment.

More Related Videos

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.1K
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

8.5K

Related Experiment Videos

Last Updated: Apr 25, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

3.1K
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.1K
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

8.5K

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Paratesticular sarcomas are rare, comprising <1% of adult sarcomas and 7-10% of intrascrotal tumors.
  • Malignant paratesticular tumors are predominantly sarcomas (90%), with subtypes including leiomyosarcoma, rhabdomyosarcoma, liposarcoma, and undifferentiated high-grade pleomorphic sarcoma.

Observation:

  • Presents two distinct cases of paratesticular sarcoma with differing clinical trajectories.
  • Case 1: Low-grade leiomyosarcoma with local recurrences and distant metastasis (cutaneous, subcutaneous, pulmonary, hepatic) 30 years post-surgery.
  • Case 2: High-grade myxoid liposarcoma with local and distant recurrence 3 years post-surgery, progressing after chemotherapy.

Findings:

  • Demonstrates the potential for late distant recurrence in low-grade paratesticular sarcomas.
  • Illustrates aggressive behavior and rapid progression in high-grade paratesticular sarcomas, even after treatment.

Implications:

  • Emphasizes the need for long-term surveillance in paratesticular sarcoma survivors due to late recurrence potential.
  • Highlights the importance of accurate histological subtyping for predicting tumor behavior and guiding treatment strategies.