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Updated: Apr 25, 2026
07:30
Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
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[Kidney paired donation. Combination with extracorporeal desensitization]
1Abteilung für Nephrologie und Dialyse, Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|August 23, 2014
Summary
Kidney exchange programs combined with desensitization allow successful kidney transplants for incompatible donor-recipient pairs. Further research is needed to optimize strategies and address ethical considerations in renal replacement therapy.
Area of Science:
- Nephrology and Transplant Surgery
- Immunology
Background:
- Live kidney donation is optimal for renal replacement therapy.
- ABO and HLA incompatibility prevent one-third of potential kidney transplants.
- Kidney exchange programs (KEPs) and desensitization offer solutions for incompatible transplants.
Purpose of the Study:
- This review examines indications, methods, ethical issues, and outcomes of KEPs.
- To provide an overview of current strategies in overcoming transplant barriers.
Main Methods:
- Comprehensive analysis of relevant Medline literature.
- Inclusion of authors' clinical experience and insights.
Main Results:
- KEPs combined with extracorporeal desensitization facilitate successful kidney transplantation for the majority of patients.
- These combined approaches significantly improve transplant rates for previously ineligible recipients.
Conclusions:
- Optimizing the combination of existing KEP and desensitization strategies is crucial.
- Addressing emerging ethical questions is essential for the advancement of paired kidney donation programs.
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