The current state of ototoxicity monitoring in New Zealand

Lotte Steffens1, Kinau Venter, Greg A O'Beirne

  • 1c/- RMO Unit, Christchurch Hospital, Riccarton Ave, Private Bag 4710, Christchurch 8140, New Zealand. Lotte.Steffens@cdhb.health.nz.

Abstract

Insights

Ototoxicity monitoring varies widely in New Zealand, with no routine follow-up post-treatment. A national guideline could improve audiological outcomes for patients receiving ototoxic chemotherapy.

Area of Science:

  • Oncology
  • Audiology
  • Pharmacovigilance

Background:

  • Ototoxic chemotherapy requires careful monitoring to prevent hearing loss.
  • Current ototoxicity monitoring practices in New Zealand are not standardized.

Purpose of the Study:

  • To assess medical oncologists' and audiologists' knowledge of ototoxicity monitoring.
  • To understand current ototoxicity monitoring protocols in New Zealand District Health Boards (DHBs).
  • To explore the need for a national ototoxicity monitoring guideline.

Main Methods:

  • Telephonic interviews were conducted with 16 audiologists and 7 medical oncologists across New Zealand DHBs.
  • Responses were analyzed to understand current practices and attitudes towards ototoxicity monitoring.

Main Results:

  • Both oncologists and audiologists demonstrated good knowledge of ototoxicity but limited familiarity with monitoring protocols.
  • Significant variability exists in ototoxicity monitoring across New Zealand DHBs, from no routine monitoring to pre-chemotherapy assessment.
  • No routine audiological follow-up is performed post-treatment, contrary to international standards.
  • 22 out of 23 participants supported the development of a national guideline.

Conclusions:

  • Discrepancies in ototoxicity monitoring across New Zealand necessitate a standardized approach.
  • Implementing a national ototoxicity monitoring protocol could enhance audiological outcomes for patients on ototoxic chemotherapy.

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