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Immunological and technical considerations in application of alginate-based microencapsulation systems

Genaro Alberto Paredes Juárez1, Milica Spasojevic2, Marijke M Faas1

  • 1Section of Immunoendocrinology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen , Groningen , Netherlands.

Frontiers in Bioengineering and Biotechnology
|August 23, 2014
PubMed
Summary

Alginate microcapsules show promise for type 1 diabetes treatment, but require further research into purity, immune response, and preclinical models for successful human application.

Keywords:
DAMPsPAMPsalginateinnate immune activationmicroencapsulationnon-human modelspurification

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