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Published on: May 2, 2019
Novel circovirus from mink, China
Abstract:
A long-established epidemic of enteritis, caused by an unidentified pathogen distinct from parvovirus, has now been recognized in mink. In 2013, we identified a novel circovirus by degenerate PCR and fully sequenced its genome. This virus differs substantially from currently known members of the genus Circovirus and represents a new species.
Insights
A novel circovirus causing enteritis in mink has been identified. This previously unknown virus represents a new species within the Circovirus genus, distinct from parvovirus.
Area of Science:
- Veterinary Virology
- Animal Pathology
Background:
- A persistent epidemic of enteritis affecting mink has been documented.
- The causative agent of this epidemic was previously unidentified and distinct from parvovirus.
Purpose of the Study:
- To identify the pathogen responsible for the enteritis epidemic in mink.
- To characterize the novel virus and determine its taxonomic classification.
Main Methods:
- Degenerate PCR was employed to detect and amplify viral genetic material.
- Full genome sequencing was performed on the identified viral isolate.
Main Results:
- A novel circovirus was identified in mink exhibiting enteritis.
- The complete genome of this circovirus was sequenced.
- Phylogenetic analysis indicated that this virus represents a new species within the genus Circovirus, substantially differing from known members.
Conclusions:
- A new circovirus species is responsible for the enteritis epidemic in mink.
- This discovery expands our understanding of circovirus diversity and its impact on animal health.
