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Growth in children with congenital diaphragmatic hernia during the first year of life

Lisette Leeuwen1, Karen Walker2, Robert Halliday2

  • 1Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, Australia; Medical School, University of Groningen, Groningen, the Netherlands.

Journal of Pediatric Surgery
|August 24, 2014
PubMed

Insights

Infants with congenital diaphragmatic hernia (CDH) experience poor early growth, but most show catch-up growth by 12 months. Close monitoring and nutritional support are crucial for these patients.

Area of Science:

  • Pediatric Surgery
  • Neonatology
  • Developmental Pediatrics

Background:

  • Congenital diaphragmatic hernia (CDH) is associated with significant mortality and long-term issues like poor growth.
  • Failure to thrive (FTT) is a common complication in infants with CDH.

Purpose of the Study:

  • To describe infant growth patterns in the first year of life for a non-Extracorporeal Membrane Oxygenation (ECMO) cohort with CDH.
  • To identify predictors of FTT in infants with CDH.

Main Methods:

  • Retrospective review of medical records for infants with CDH (2005-2011).
  • Inclusion of infants with anthropometric measurements at 3, 6, and 12 months.
  • Logistic regression analysis to determine predictors of FTT.

Main Results:

  • Poor growth, particularly weight, was observed in 63% of survivors within the first six months.
  • Mechanical ventilation duration was the sole predictor of FTT.
  • Catch-up growth occurred in the latter half of infancy, reducing FTT to 21% by 12 months.

Conclusions:

  • Early poor growth is prevalent in CDH infants but tends to improve.
  • Close follow-up and proactive nutritional management are essential for CDH patients.
Abstract

Keywords:
Congenital diaphragmatic herniaFailure to thriveGrowthHeightWeight

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