Related Experiment Video
Updated: Apr 25, 2026
10:52
Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
7.7K
Percutaneous transcatheter PDA device closure in infancy
Maad Ullah1, Mehboob Sultan1, Khurram Akhtar1
1Department of Paediatrics Cardiology, Armed Forces Institute of Cardiology / National Institute of Heart Diseases (AFIC/NIHD), Rawalpindi.
Summary
Transcatheter device closure is effective for patent ductus arteriosus (PDA) in infants, but local vascular complications are common. This study evaluated outcomes and issues in infant PDA closure.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Neonatal Medicine
Background:
- Patent ductus arteriosus (PDA) is a common congenital heart defect in infants.
- Transcatheter closure offers a minimally invasive alternative to surgical intervention for PDA.
Purpose of the Study:
- To assess the efficacy and safety of transcatheter device closure for PDA in infants.
- To identify and analyze complications associated with the procedure.
Main Methods:
- A quasi-experimental study involving infants undergoing transcatheter PDA closure.
- Pre-procedural evaluation using 2-D echocardiography and Doppler by pediatric cardiologists.
- Recording of procedural success rates and any occurring complications.
Main Results:
- Successful transcatheter closure was achieved in 96.1% of eligible infants (50 out of 52).
- Complications included acquired coarctation in one infant and non-fatal cardiac arrest during device deployment in another.
- Local vascular access site complications occurred in 21.8% of cases but were managed successfully.
Conclusions:
- Transcatheter device closure is a largely effective treatment for PDA in infants.
- A significant incidence of local vascular complications necessitates careful monitoring and management.
