Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Thyroid Function Parameters, Thyroid Status, and Vitamin B12 Deficiency in Hospitalized Adults: A Retrospective Cross-Sectional Study in Eastern India.

Cureus·2026

Same author

Identifying and targeting abnormal mitochondrial localization associated with psychosis.

bioRxiv : the preprint server for biology·2026

Same author

Assessing Potential Data Sources for Landscape-scale Terrestrial Biodiversity Indicators.

Environmental management·2026

Same author

Phenotypic screening for small molecules that lower PrP in cultured cells.

bioRxiv : the preprint server for biology·2026

Same author

Progress and new challenges in image-based profiling.

Molecular systems biology·2026

Same author

Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes.

Cell systems·2026

Search research articles

Related Experiment Video

Updated: Apr 25, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

ProtocolNavigator: emulation-based software for the design, documentation and reproduction biological experiments.

Imtiaz A Khan¹, Adam Fraser², Mark-Anthony Bray²

¹School of Medicine, Cardiff University, Cardiff, UK, Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA and School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK School of Medicine, Cardiff University, Cardiff, UK, Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA and School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK.

Bioinformatics (Oxford, England)

|August 24, 2014

Summary

This summary is machine-generated.

ProtocolNavigator is a new open-source software tool designed to improve the reproducibility of biological experiments. It helps researchers easily design, document, and reproduce complex experimental methodologies, enhancing scientific progress.

More Related Videos

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

Related Experiment Videos

Last Updated: Apr 25, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

Area of Science:

Biological Sciences
Bioinformatics
Scientific Research

Background:

Experimental reproducibility is crucial for scientific advancement and efficient drug discovery.
Irreproducible research hinders progress by decreasing efficiency and impeding data reuse.
Current bioinformatics tools often focus on computational reproducibility or lab management, neglecting experimental design interpretation.

Purpose of the Study:

To introduce ProtocolNavigator, a novel software tool addressing the challenges of interpreting and assessing biological experimental methodologies.
To provide a biologist-friendly, open-source solution for designing, documenting, and reproducing biological experiments.

Main Methods:

ProtocolNavigator was developed using Python 2.7 with a wx module for its graphical user interface.
The software is platform-independent, ensuring broad accessibility for researchers.
It employs an emulation-based approach to facilitate experiment design and reproduction.

Main Results:

ProtocolNavigator offers a user-friendly interface for biologists to manage experimental protocols.
The tool aids in clarifying complex experimental designs, thereby reducing ambiguity.
It facilitates the assessment of variations across different experiments, promoting reproducibility.

Conclusions:

ProtocolNavigator provides a valuable solution for enhancing the reproducibility of biological experiments.
The software's open-source and biologist-friendly nature promotes wider adoption and collaboration.
By improving the interpretation and documentation of experimental methods, ProtocolNavigator contributes to more efficient and reliable scientific research.