Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Seizures l: Introduction01:20

Seizures l: Introduction

30
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
30
Seizures: Classification01:13

Seizures: Classification

2.4K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
2.4K
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.7K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.7K
Epilepsy ll: Types01:22

Epilepsy ll: Types

27
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
27
Seizures ll: Types01:19

Seizures ll: Types

25
Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
25
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

1.3K
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discrepancies in Inter-Rater Agreement on Resectability of Recurrent Glioblastoma: Complementary Post-hoc Analysis of the Prospective, Randomized DIRECTOR Trial.

Neuro-oncology·2026
Same author

Shape features of white matter tracts associated with post-surgical speech production outcomes.

Brain and language·2026
Same author

Spinal infection: an evolving clinical and public health challenge.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Patient-derived organoids and neurospheres recapitulate salient features of primary tumor heterogeneity.

Neuro-oncology advances·2026
Same author

Brain tissue oxygen monitoring for severe traumatic brain injury: the international multicentre randomised controlled BONANZA-GT study protocol.

BMJ open·2025
Same author

Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial.

Nature medicine·2025

Related Experiment Video

Updated: Apr 25, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K

Brain tumour-associated status epilepticus.

Janindu Goonawardena1, Laurence A G Marshman2, Katharine J Drummond3

  • 1Cairns Clinical School, School of Medicine, James Cook University, Cairns Hospital, Cairns, QLD 4870, Australia.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|August 25, 2014
PubMed
Summary

Status epilepticus in brain tumor patients (TASE) is less common than in the general population (SEGP). TASE occurs later in disease, is linked to high-grade tumors, and paradoxically responds better to simple anti-epileptic drug regimens.

Keywords:
Brain tumourStatus epilepticusTumour associated epilepsy

More Related Videos

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.1K
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
08:47

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

11.2K

Related Experiment Videos

Last Updated: Apr 25, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.1K
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
08:47

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

11.2K

Area of Science:

  • Neurology
  • Oncology

Background:

  • Epilepsy is a common complication of brain tumors.
  • Status epilepticus (SE) is a rare but serious neurological emergency.

Observation:

  • Patients with brain tumor-associated epilepsy (TAE) are less prone to status epilepticus (TASE) than epilepsy in the general population (SEGP).
  • TASE often occurs later in the disease course, unlike TAE which presents early.
  • TASE is associated with high-grade gliomas, contrasting with TAE where risk decreases with tumor grade.

Findings:

  • TASE shows paradoxical responsiveness to simple anti-epileptic drug (AED) regimens compared to TAE and SEGP.
  • Mortality in TASE is likely influenced by the underlying brain tumor, similar to SEGP.
  • TASE exhibits a distinct clinical profile compared to TAE and SEGP.

Implications:

  • Understanding TASE's unique characteristics is crucial for patient management.
  • Further multi-center, prospective studies are needed to confirm these preliminary findings.
  • This research highlights the need for tailored epilepsy management strategies in brain tumor patients.