Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential Plasma Expression of sTNF-R, TNF-α, PDGF-AA, IL-17A, and IL-1β Across the Colorectal Neoplasia Spectrum.

Biomolecules·2026
Same author

Serum Behavior of NT-3 and VEGFβ, Two Unstudied Growth Factors in Patients with Diabetes Mellitus and End-Stage Renal Disease.

Journal of clinical medicine·2025
Same author

The Impact of Physical Form on the Biocompatibility of Poly(3-hexylthiophene-2,5-diyl).

Materials (Basel, Switzerland)·2025
Same author

Unexpectedly High and Difficult-to-Explain Regenerative Capacity in an 82-Year-Old Patient with Insulin-Requiring Type 2 Diabetes and End-Stage Renal Disease.

Journal of clinical medicine·2025
Same author

Hydrodynamic Stokes flow induced by a chemically active patch imprinted on a planar wall.

Journal of colloid and interface science·2025
Same author

A Preliminary Stability Assessment of Three State-of-the-Art CAD/CAM Materials Under Human Gingival Cell Culture.

Polymers·2025

Related Experiment Video

Updated: Apr 25, 2026

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
09:43

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

14.6K

Magneto-plasmonic biosensor with enhanced analytical response and stability.

Sorin David1, Cristina Polonschii1, Catalin Luculescu2

  • 1International Centre of Biodynamics, Intrarea Portocalelor 1B, Bucharest 060101, Romania.

Biosensors & Bioelectronics
|August 25, 2014
PubMed
Summary

We developed a new Magneto-Optical Surface Plasmon Resonance (MOSPR) chip and analysis method. This enhances sensitivity and stability for detecting low analyte concentrations in liquid media.

Keywords:
Affinity biosensorAngle-resolved surface plasmon resonanceFixed-angle surface plasmon resonanceMagnetic alloysMagneto-optic surface plasmon resonanceSurface plasmon resonance enhancement

More Related Videos

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

7.7K
Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures
08:01

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Published on: November 21, 2019

6.6K

Related Experiment Videos

Last Updated: Apr 25, 2026

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
09:43

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

14.6K
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

7.7K
Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures
08:01

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Published on: November 21, 2019

6.6K

Area of Science:

  • Nanotechnology
  • Biophysics
  • Analytical Chemistry

Background:

  • Current Magneto-Optical Surface Plasmon Resonance (MOSPR) assays face analytical limitations.
  • Existing MOSPR chip structures and data analysis methods require improvement for enhanced sensitivity and stability.

Purpose of the Study:

  • To introduce novel solutions for Magneto-Optical Surface Plasmon Resonance (MOSPR) assays.
  • To overcome current limitations in chip structure and data analysis for MOSPR.

Main Methods:

  • Modified chip structure using a Co-Au alloy layer for improved plasmonic and magnetic properties.
  • Developed a data analysis method evaluating the entire reflectivity curve at multiple incidence angles.
  • Assessed performance using solutions with known refractive indices and a model biomolecular interaction (IgG-AntiIgG).

Main Results:

  • The Co-Au alloy chip demonstrated structural stability suitable for bioaffinity assays in saline solutions.
  • The new analysis method provided a high signal-to-noise ratio, enabling detection of minute analyte concentrations.
  • Demonstrated increased sensitivity and long-time assessment capability in liquid media compared to standard Surface Plasmon Resonance (SPR) analyses.

Conclusions:

  • The proposed MOSPR sensing chip structure and data analysis procedure significantly enhance assay performance.
  • The advancements allow for more sensitive and stable detection of biomolecular interactions in liquid environments.
  • This work paves the way for improved biosensing applications using MOSPR technology.