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The Ratio of X Chromosome to Autosomes

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...

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Updated: Apr 25, 2026

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development

Published on: January 26, 2013

Hox transcriptomics in Drosophila embryos.

Maria Polychronidou¹, Ingrid Lohmann

¹Centre for Organismal Studies (COS) Heidelberg, University of Heidelberg, Im Neuenheimer Feld 267, 69120, Heidelberg, Germany.

Methods in Molecular Biology (Clifton, N.J.)

|August 25, 2014

Summary

This summary is machine-generated.

This study identifies Hox downstream genes in Drosophila embryos using microarray analysis. Understanding these gene networks is crucial for deciphering how Hox transcription factors control development.

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Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

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Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

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Published on: September 20, 2014

Area of Science:

Developmental Biology
Genetics
Molecular Biology

Background:

Hox proteins are key transcription factors controlling animal development.
They specify segment identity along the anteroposterior axis in bilaterians.
Understanding Hox-regulated gene networks is vital for developmental mechanisms.

Purpose of the Study:

To describe a method for quantitatively identifying Hox downstream genes.
To analyze the Hox transcriptome in Drosophila embryos.

Main Methods:

Utilizing high-throughput whole-transcriptome mRNA expression profiling.
Performing Hox transcriptome analysis using microarrays in Drosophila embryos.

Main Results:

Quantitative identification of Hox downstream genes was achieved.
The study provides a framework for dissecting Hox-regulated transcriptional networks.

Conclusions:

Microarray-based Hox transcriptome analysis is an effective tool.
This approach facilitates the genome-wide identification of Hox target genes.