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Updated: Apr 25, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Bilateral coronary ostial stenosis secondary to syphilitic aortitis
Zhaoping Cheng1, Shihua Zhao2, Wanli Bi1
1Department of Radiology, Shandong Medical Imaging Research Institute, Shandong University, Jingwu Road No 324, Jinan 250021, China.
Insights
Cardiovascular syphilis can cause serious aortic and coronary artery issues. This case highlights syphilitic aortitis leading to coronary ostial stenosis and aortic regurgitation, successfully treated with bypass surgery.
Area of Science:
- Cardiology
- Infectious Diseases
- Syphilology
Background:
- Cardiovascular syphilis, a tertiary syphilis manifestation, affects the ascending aorta.
- It can lead to severe complications like aortic aneurysm, aortic regurgitation, and coronary ostial stenosis.
Observation:
- A case of syphilitic aortitis presenting with bilateral coronary ostial stenosis and aortic regurgitation is reported.
- The patient's condition was diagnosed through clinical evaluation and diagnostic imaging.
Findings:
- Syphilitic aortitis was identified as the cause of bilateral coronary ostial stenosis.
- Aortic regurgitation was also a significant finding in this patient.
Implications:
- Surgical intervention, specifically coronary artery bypass graft, can effectively manage these cardiovascular complications.
- Early diagnosis and treatment of cardiovascular syphilis are crucial to prevent irreversible damage.
Abstract:
Cardiovascular syphilis is associated with the tertiary stage of syphilis infection; it involves the ascending aorta and can cause aortic aneurysm, aortic regurgitation, and coronary ostial stenosis. We report here a case in which bilateral coronary ostial stenosis and aortic regurgitation due to syphilitic aortitis was diagnosed; coronary artery bypass graft was then performed.
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