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Related Experiment Video

Updated: Apr 25, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

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[Tuberculoid leprosy revealed by active ulcerative colitis: a case report].

M G Diop1, B A Diatta2, A Berthe3

  • 1Université de Thiès, UFR des Sciences de la santé, Thiès, Sénégal.

Medecine Et Sante Tropicales
|August 26, 2014
PubMed
Summary

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Tuberculoid leprosy, a skin and nerve disease, can present with ulcerative colitis. Effective treatment for leprosy also led to remission of colitis in a Senegalese patient.

Area of Science:

  • Dermatology
  • Gastroenterology
  • Infectious Diseases

Background:

  • Leprosy is endemic in Senegal, with 73 new cases reported in Dakar in 2011.
  • Discovery of leprosy often involves dermatologic or neurologic symptoms.
  • Associations between leprosy and chronic inflammatory colitis are rarely reported and often considered coincidental.

Observation:

  • A 30-year-old woman presented with active ulcerative colitis that revealed tuberculoid leprosy.
  • The patient's leprosy was diagnosed as tuberculoid type.

Findings:

  • Treatment followed the World Health Organization (WHO) leprosy protocol.
  • Corticosteroids and methotrexate were used in conjunction with the WHO protocol.
  • The combined treatment resulted in the healing of leprosy.
Keywords:
Senegalchronic ulcerative colitiscorticosteroidsleprosy

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Last Updated: Apr 25, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
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Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

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  • The treatment also led to remission of the ulcerative colitis.
  • Implications:

    • This case highlights a potential, though likely fortuitous, association between tuberculoid leprosy and ulcerative colitis.
    • Successful management of leprosy can positively impact concurrent inflammatory bowel conditions.
    • Further research may explore any underlying immunologic links between these conditions.