[Optimizing scan protocol in whole-brain vessel one-stop examination with 640-multislice computed tomography].

Area of Science:

• Radiology
• Medical Imaging
• Radiation Oncology

Background:

• Whole-brain vessel examination is crucial for diagnosing cerebrovascular diseases.
• 640-multislice computed tomography (640-MSCT) scanners offer advanced imaging capabilities.
• Optimizing scan protocols is essential for reducing radiation exposure in medical imaging.

Purpose of the Study:

• To evaluate the feasibility of an optimized scan protocol for whole-brain vessel examination using a 640-MSCT scanner.
• To assess the impact of an optimized protocol on radiation dose, CT perfusion (CTP) values, and CT angiography (CTA) image quality.

Main Methods:

• A comparative study involving 28 patients divided into two groups: one using the recommended protocol (19 volumes) and another using an optimized protocol (15 volumes).
• Radiation dose was measured by dose length product (DLP) and effective dose (E).
• CTP values and CTA image quality were analyzed and compared between the two groups using statistical analysis.

Main Results:

• The optimized protocol group showed a 19.23% reduction in DLP compared to the recommended protocol group.
• No statistically significant differences were observed in relative perfusion values or parameters between the groups (P > 0.05).
• Image quality of CTA was comparable between the two groups, with no statistically significant differences (P > 0.05).

Conclusions:

• The optimized scan protocol for whole-brain vessel examination using 640-MSCT effectively reduces radiation dose.
• This optimization is achieved without compromising the accuracy of perfusion parameters or the quality of CTA images.
• The optimized protocol holds significant clinical importance for patient safety and efficient diagnostic imaging.