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Updated: Feb 11, 2026

Synthesis and Characterization of Amphiphilic Gold Nanoparticles
Published on: July 2, 2019
Synthesis of 5-Substituted Derivatives of Isophthalic Acid as Non-Polymeric Amphiphilic Coating for Metal Oxide
Denis Nilov1, Pavel Kucheryavy1, Verina Walker1
1Xavier University, Chemistry Department, New Orleans, Louisiana 70125, USA.
Abstract:
In the course of development of novel capping ligands with variable steric factor, which will be used as an organic coating for metal oxide nanoparticles, a base-catalyzed nucleophilic oxirane ring-opening addition reaction between dimethyl 5-hydroxyisophthalate and allyl glycidyl ether was studied. The allyl-terminated 1-1, 1-2 and 1-3 adducts and dihydroxylated derivative of the 1-1 adduct, 5-diglyceroxy isophthalic acid, were synthesized. The latter binds to the surface of 5 nm γ-Fe2O3 nanoparticles in reaction with their surfactant-free diethylene glycol colloids.
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