Patient-reported outcomes in obsessive-compulsive disorder
Mythily Subramaniam1, Pauline Soh1, Clarissa Ong1
1Research Division, Institute of Mental Health, Singapore.
Dialogues in Clinical Neuroscience
|August 26, 2014
Summary
Patient-reported outcomes (PROs) in obsessive-compulsive disorder (OCD) show significant functional disability and lower quality of life. Patient-reported outcome measures (PROMs) effectively track symptom changes and predict treatment success.
Area of Science:
- Psychiatry
- Clinical Psychology
- Health Outcomes Research
Background:
- Obsessive-compulsive disorder (OCD) significantly impacts patients' daily lives.
- Assessing patient-reported outcomes (PROs) is crucial for understanding treatment effectiveness.
Purpose of the Study:
- To review patient-reported outcome measures (PROMs) for functioning, health-related quality of life (HRQoL), and OCD symptoms.
- To evaluate the utility of PROMs in OCD research and clinical practice.
Main Methods:
- Systematic review of 155 unique articles.
- Identification and analysis of 22 distinct PROMs used in OCD studies.
Main Results:
- OCD patients experience substantial functional disability and reduced HRQoL compared to controls.
- PROMs demonstrate sensitivity to change and may outperform clinician-rated measures in predicting treatment outcomes.
- A notable limitation is the lack of patient input in the development of reviewed PROMs.
Conclusions:
- PROMs are valuable tools for assessing outcomes in OCD.
- Future PROMs development must incorporate patient perspectives and undergo rigorous psychometric validation.
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