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Updated: Apr 25, 2026

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
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What vibrations tell us about GTPases.

Carsten Kötting, Klaus Gerwert

    Biological Chemistry
    |August 26, 2014
    PubMed
    Summary

    Time-resolved Fourier transform infrared (FTIR) spectroscopy reveals the atomic details of GTP hydrolysis catalyzed by small GTPases and their activating proteins. This method illuminates disease-related mechanisms and catalytic processes at the membrane.

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