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[Effect of subclinical hypothyroidism treatment on selected cardiovascular parameters]

Michał Krysicki, Ewa Slusarczyk, Bozena Popowicz

    Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
    |August 27, 2014
    PubMed

    Insights

    Subclinical hypothyroidism (SH) treatment with L-thyroxine normalized cardiac irregularities in some patients. This normalization improved systolic and diastolic functions and reduced arrhythmias, positively impacting cardiovascular health.

    Area of Science:

    • Cardiology
    • Endocrinology

    Context:

    • Subclinical hypothyroidism (SH) impact on cardiovascular health is unclear.
    • Treatment indications for SH remain debated.

    Purpose:

    • To analyze L-thyroxine therapy effects on cardiac irregularities in SH patients.
    • To evaluate normalization of thyroid-stimulating hormone (TSH) on cardiac parameters.

    Summary:

    • 25 SH patients and 25 controls underwent physical, ECG, and echocardiographic exams.
    • SH patients showed more irregularities, particularly in resting ECG and echocardiography.
    • Six-month L-thyroxine treatment normalized TSH, improving cardiac function and reducing arrhythmias.

    Impact:

    • TSH normalization positively affects cardiac parameters in some SH patients.
    • Treatment improved left ventricular systolic and diastolic functions.
    • Reduced arrhythmias and a correlation between TSH levels and arrhythmia frequency were observed.
    Abstract

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