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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

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Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
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Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

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Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

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Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
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Related Experiment Video

Updated: Apr 25, 2026

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
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[Chronic diarrhea].

Teresa Stelzer1, Ludwig Theodor Heuss2

  • 1Medizinische Klinik, Spital Zollikerberg, Zollikerberg und Abteilung für Gastroenterologie und Hepatologie, Stadtspital Triemli, Zürich.

Therapeutische Umschau. Revue Therapeutique
|August 27, 2014
PubMed
Summary

Chronic diarrhoea, lasting over four weeks, requires careful patient history and examination for effective evaluation. Functional diarrhoea is the most common cause in developed nations, often linked to motility issues.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Medicine

Context:

  • Chronic diarrhoea is a prevalent and complex clinical issue.
  • Patient perception of diarrhoea varies significantly.
  • Effective management necessitates a thorough diagnostic approach.

Purpose:

  • To outline the essential components for evaluating chronic diarrhoea.
  • To highlight the prevalence of functional diarrhoea and motility disorders.
  • To emphasize the utility of stool characteristics in guiding investigations.

Summary:

  • Chronic diarrhoea evaluation hinges on detailed history, physical examination, and strategic investigations.
  • Functional diarrhoea is the leading cause in developed countries, surpassing inflammatory, osmotic, or secretory origins.

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  • Motility disorders are more frequent causes than other specific types.

    • Impact:

    • Provides a framework for clinicians managing chronic diarrhoea.
    • Improves diagnostic accuracy by focusing on common causes and key indicators.
    • Enhances patient care through a structured and evidence-based evaluation process.