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Recurrent furunculosis in returning travelers: newly defined entity
Ofir Artzi1, Maya Sinai, Michal Solomon
1Department of Dermatology, Chaim Sheba Medical Center, Ramat Gan, Israel.
Journal of Travel Medicine
|August 27, 2014
Summary
Post-travel recurrent furunculosis (PTRF) is a distinct condition characterized by recurring boils after tropical travel. Methicillin-sensitive Staphylococcus aureus (MSSA) is the common cause, with recovery linked to immune system normalization.
Area of Science:
- Dermatology
- Infectious Diseases
- Travel Medicine
Background:
- Bacterial skin infections are common in travelers.
- Post-travel recurrent furunculosis (PTRF) is a unique condition of sequential furuncles after tropical travel.
- PTRF presents as multiple furuncles occurring after returning from a trip.
Purpose of the Study:
- To characterize the disease course of PTRF.
- To investigate potential causes of PTRF.
Main Methods:
- Retrospective study of young, healthy individuals with PTRF.
- Analysis of disease duration, recurrence patterns, and bacterial cultures.
- Assessment of Staphylococcus aureus nasal colonization.
Main Results:
- The average duration of PTRF was 8.4 months with 4.2 recurrences.
- Methicillin-sensitive Staphylococcus aureus (MSSA) was the most common pathogen (76.5%).
- Nasal colonization with MSSA was found in 47% of patients; recurrences became milder over time.
Conclusions:
- PTRF is a clinical entity with prolonged tropical travel as a major risk factor.
- A transient immune alteration in travelers may trigger recurrent furuncles.
- Resolution of PTRF is associated with the restoration of normal immunity.
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