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Recurrent furunculosis in returning travelers: newly defined entity

Ofir Artzi1, Maya Sinai, Michal Solomon

  • 1Department of Dermatology, Chaim Sheba Medical Center, Ramat Gan, Israel.

Journal of Travel Medicine
|August 27, 2014
PubMed
Abstract

Insights

Post-travel recurrent furunculosis (PTRF) is a distinct condition characterized by recurring boils after tropical travel. Methicillin-sensitive Staphylococcus aureus (MSSA) is the common cause, with recovery linked to immune system normalization.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Travel Medicine

Background:

  • Bacterial skin infections are common in travelers.
  • Post-travel recurrent furunculosis (PTRF) is a unique condition of sequential furuncles after tropical travel.
  • PTRF presents as multiple furuncles occurring after returning from a trip.

Purpose of the Study:

  • To characterize the disease course of PTRF.
  • To investigate potential causes of PTRF.

Main Methods:

  • Retrospective study of young, healthy individuals with PTRF.
  • Analysis of disease duration, recurrence patterns, and bacterial cultures.
  • Assessment of Staphylococcus aureus nasal colonization.

Main Results:

  • The average duration of PTRF was 8.4 months with 4.2 recurrences.
  • Methicillin-sensitive Staphylococcus aureus (MSSA) was the most common pathogen (76.5%).
  • Nasal colonization with MSSA was found in 47% of patients; recurrences became milder over time.

Conclusions:

  • PTRF is a clinical entity with prolonged tropical travel as a major risk factor.
  • A transient immune alteration in travelers may trigger recurrent furuncles.
  • Resolution of PTRF is associated with the restoration of normal immunity.

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