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Updated: Apr 25, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep-disordered breathing in neurologic conditions.
Maryann C Deak1, Douglas B Kirsch1
1Division of Sleep and Circadian Disorders, Departments of Neurology and Medicine, Brigham and Women's Hospital, Boston, MA, USA; Department of Neurology, Harvard Medical School, Boston, MA, USA.
Sleep-disordered breathing (SDB), including central sleep apnea and obstructive sleep apnea, is common in neurologic conditions. Recognizing and treating SDB is crucial for managing patients with neurological disease.
Area of Science:
- Neurology
- Sleep Medicine
- Respiratory Medicine
Background:
- Sleep-disordered breathing (SDB) is prevalent in patients with neurological conditions.
- Neurological diseases can impair respiratory control and increase SDB risk through various mechanisms.
- Factors contributing to SDB in this population include muscular weakness, central respiratory drive impairment, sedating medications, and inactivity-related weight gain.
Purpose of the Study:
- To highlight the importance of recognizing sleep-disordered breathing in patients with neurologic conditions.
- To discuss the key aspects of diagnosing and managing SDB within the context of neurological disease.
Main Methods:
- This article provides a review of the literature and clinical considerations regarding SDB in neurologic disease.
- It focuses on the interplay between neurological function and respiratory control during sleep.
Main Results:
- SDB is a common comorbidity in various neurologic disorders.
- Patients with neurologic conditions face unique risk factors for developing SDB.
- Effective management of SDB can positively impact the overall health outcomes of patients with neurological diseases.
Conclusions:
- Recognition and timely treatment of SDB are essential components of comprehensive care for patients with neurologic conditions.
- Addressing SDB can mitigate associated risks and improve patient quality of life.
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