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A new formula for premature infants: effects on growth and nutritional status

Lucia Marseglia1, Giuseppina Pagano, Alessandro Arco

  • 1a Neonatal Intensive Care Unit, Department of Pediatrics , University of Messina , Messina , Italy .

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|August 27, 2014
PubMed

Insights

Preterm infant formula (PTF) provides similar growth and nutritional benefits compared to fortified human milk (FHM) in premature infants. This study found Nutribèn Pre to be a safe and effective alternative for preterm infant nutrition.

Area of Science:

  • Neonatal Nutrition
  • Pediatric Gastroenterology
  • Infant Development

Background:

  • Nutritional management is critical for the survival, growth, and development of low birth weight and very low birth weight infants.
  • Preterm infant formula (PTF) serves as a crucial alternative when mother's milk or donor milk is insufficient or unavailable.
  • Evaluating specialized formulas is essential for optimizing outcomes in premature infants.

Purpose of the Study:

  • To assess the short-term effects of a new preterm infant formula (Nutribèn Pre) on the nutritional status of premature infants.
  • To compare auxological and biochemical parameters between infants fed Nutribèn Pre and those fed fortified human milk (FHM).

Main Methods:

  • A prospective, multicenter study involving 97 preterm infants (500-2000g birth weight, 25-34 weeks postmenstrual age).
  • Infants were randomly assigned to receive either the new preterm infant formula (Nutribèn Pre) or fortified human milk (FHM).
  • Nutritional status was evaluated using auxological and biochemical parameters.

Main Results:

  • No significant differences were found in growth parameters between the Nutribèn Pre and FHM groups.
  • Feeding tolerance showed no significant variations between the two feeding regimens.
  • Biochemical profiles remained comparable across both groups, indicating similar nutritional status.

Conclusions:

  • The preterm infant formula, Nutribèn Pre, is a viable and safe option for nourishing premature infants.
  • Nutribèn Pre demonstrates comparable efficacy to fortified human milk in supporting short-term nutritional status.
  • This study supports the use of Nutribèn Pre as an effective alternative in preterm infant feeding.
Abstract

Keywords:
Human milknutritional statuspreterm infant formula

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