Blood pressure values and depression in hypertensive individuals at high cardiovascular risk

Cilia Mejia-Lancheros, Ramón Estruch, Miguel Angel Martínez-González

  • 1Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. mamunoz.bcn.ics@gencat.cat.

Insights

Hypertension and depression are linked to cardiovascular disease risk. This study found that hypertensive patients with depression had better blood pressure control, regardless of antidepressant treatment.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Hypertension and depression are significant risk factors for cardiovascular diseases (CVDs).
  • The precise relationship between blood pressure control and depression remains incompletely understood.
  • This research investigates the influence of depression on blood pressure management in high-risk hypertensive individuals.

Purpose of the Study:

  • To determine if depression impacts blood pressure control in hypertensive patients with elevated cardiovascular risk.
  • To analyze the association between depression and blood pressure control metrics.

Main Methods:

  • A cross-sectional study involving 5954 hypertensive patients with high cardiovascular risk profiles was conducted.
  • Data was collected as part of the PREDIMED clinical trial.
  • Multivariate regression analyses, including logistic and log-linear models, were employed, adjusting for various confounders.

Main Results:

  • Depressive patients, both treated and untreated for depression, exhibited superior blood pressure control compared to non-depressive individuals.
  • Systolic blood pressure levels were significantly lower in depressive patients (treated and untreated).
  • Odds ratios for better blood pressure control were 1.28 (CI 95%: 1.06-1.55) for treated and 1.30 (CI 95%: 1.03-1.65) for untreated depressive patients.

Conclusions:

  • Hypertensive patients at high cardiovascular risk who are diagnosed with depression demonstrate improved blood pressure control.
  • Depression may play a role in achieving better blood pressure management in this patient population.
Abstract

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