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Updated: Apr 25, 2026

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
Published on: April 26, 2024
Focusing neurovisceral integration: cognition, heart rate variability, and cerebral blood flow
J Richard Jennings1,2, Ben Allen1,2, Peter J Gianaros1,2
1Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Abstract:
The neurovisceral integration hypothesis suggests in part that cerebral control of autonomic function conveys comparable control of executive function and, hence, correlation among vagally determined high frequency heart rate variability (HF-HRV), executive function, and regional cerebral blood flow (CBF). In 440 middle-aged men and women, resting HF-HRV was related to regional CBF derived from a resting arterial spin-labeled MRI scan and to seven neuropsychological tests of executive function. Despite some intercorrelations, regression modeling failed to support integrated central control of HF-HRV and executive function. Integration between autonomic and cognitive control appears more circumscribed than the general integration suggested by the neurovisceral integration hypothesis.
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