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Time-based physical activity interventions for weight loss: a randomized trial.

John M Jakicic1, Amy D Rickman, Wei Lang

  • 11Department of Health and Physical Activity, Physical Activity and Weight Management Research Center, University of Pittsburgh, Pittsburgh, PA; 2Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University, Winston-Salem, NC; and 3Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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Summary
This summary is machine-generated.

The MAINTAIN strategy, delivering enhanced weight loss interventions later in the program, significantly improved 18-month weight loss and fitness compared to standard behavioral weight loss programs.

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Area of Science:

  • Obesity Research
  • Behavioral Medicine
  • Clinical Trials

Background:

  • Standard behavioral weight loss programs (SBWP) often yield modest long-term results.
  • Enhancing interventions with additional strategies may improve weight loss outcomes.
  • Timing of intervention delivery is a critical factor in long-term success.

Purpose of the Study:

  • To evaluate if enhancing SBWP with additional strategies at intervention initiation (ADOPT) or later (MAINTAIN) improves 18-month weight loss.
  • To compare the efficacy of ADOPT and MAINTAIN strategies against SBWP.
  • To assess the impact on participant fitness levels.

Main Methods:

  • A randomized clinical trial involving 195 overweight and obese adults.
  • Participants were assigned to SBWP, ADOPT, or MAINTAIN groups for 18 months.
  • Interventions included diet, physical activity, and group sessions, with ADOPT and MAINTAIN receiving additional tailored support.

Main Results:

  • The MAINTAIN group showed significantly greater 18-month weight loss compared to SBWP and ADOPT.
  • MAINTAIN participants achieved 9.0 ± 1.2 kg weight loss, compared to 5.9 ± 1.2 kg (SBWP) and 5.8 ± 1.2 kg (ADOPT).
  • Significant improvements in fitness were observed in the MAINTAIN group, particularly compared to ADOPT.

Conclusions:

  • The MAINTAIN strategy, emphasizing physical activity later in the intervention, enhances long-term weight loss and fitness.
  • Time-based delivery of enhanced strategies is crucial for maximizing benefits in weight management.
  • Findings offer valuable insights for implementing effective, long-term weight loss and fitness interventions.