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Updated: Aug 11, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
Published on: July 9, 2020
Continuous monitoring of ventilation in spontaneously breathing anesthetized rats
1Department of Pharmacology and Toxicology, University of Helsinki, Finland.
Abstract:
A method for continuous monitoring and recording of ventilation rate and tidal volume in spontaneously breathing anesthetized rats is described. The system is based on a hot wire flow meter placed in connection with the tracheotomy tube. In cardiovascular experiments routine monitoring of ventilation was found useful in the following instances: 1) detection of ventilatory disorders, 2) detection of central effects of drugs, 3) interpretation of results in cases where cardiovascular drugs alter ventilatory function.

