Metastatic prostate cancer to the duodenum: a rare case

Area of Science:

• Oncology
• Gastroenterology
• Radiology

Background:

• Prostate cancer is a common malignancy in men, with varied behavior from localized tumors to aggressive metastatic disease.
• Metastasis commonly occurs in bone, but rare sites include the small bowel.
• Early detection and awareness of rare metastatic patterns are crucial for patient management.

Observation:

• This report details a rare case of metastatic prostate cancer presenting in the duodenum.
• Literature review identified only two previous cases of duodenal prostate metastases since 1966.
• This represents the third documented case of duodenal metastasis from prostate cancer.

Findings:

• Prostate cancer can present with unusual distant metastases, even without local lymphadenopathy.
• Small intestine metastasis in advanced prostate cancer, though rare, should be considered in symptomatic patients.
• Radiological and clinical awareness is vital for diagnosing these uncommon presentations.

Implications:

• This case expands the known spectrum of prostate cancer metastasis.
• Clinicians and radiologists should consider duodenal metastasis in advanced prostate cancer patients with gastrointestinal symptoms.
• Increased awareness may lead to earlier diagnosis and improved management of rare metastatic prostate cancer presentations.