Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Disorders01:29

Bone Disorders

7.9K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
7.9K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.2K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.2K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

1.3K
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.3K
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

1.0K
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
1.0K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

918
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
918
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

12
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
12

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving nutritional assessment in pediatric anorexia nervosa: Clinical value of key serum biomarkers.

Journal of pediatric gastroenterology and nutrition·2026
Same author

Correlation Between Osseous Degenerative Changes on Cone Beam Computed Tomography and Disc Displacement on Magnetic Resonance Imaging in Temporomandibular Joint Osteoarthritis.

Acta stomatologica Croatica·2026
Same author

Clinical and dGEMRIC Evaluation of Microfragmented Adipose Tissue Versus Hyaluronic Acid in Inflammatory Phenotype of Knee Osteoarthritis: A Randomized Controlled Trial.

Biomedicines·2025
Same author

The Use of the Modified Brixia Score for Predicting Mortality and Acute Respiratory Distress Syndrome in Patients with COVID-19 Pneumonia: What Have We Learned?

Diagnostics (Basel, Switzerland)·2025
Same author

Ceftriaxone-loaded albumin-based nanoparticles incorporated into in situ ionic sensitive nasal gels: Development, characterization, and nasal drug deposition studies.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2025
Same author

Double Trouble on the Lower Leg-Unique Human Coinfection with <i>Echinococcus granulosus</i> and <i>Echinococcus multilocularis</i> Without Liver Involvement.

Pathogens (Basel, Switzerland)·2025

Related Experiment Videos

Sever's disease complicated with osteomyelitis.

Matej Mustapić, Igor Borić, Dragan Lepur

    Acta Clinica Croatica
    |August 29, 2014
    PubMed
    Summary

    Sever's disease, a common cause of heel pain in young athletes, can rarely be complicated by calcaneal osteomyelitis. Early MRI is crucial for diagnosing this rare complication and guiding treatment.

    Area of Science:

    • Pediatric Orthopedics
    • Radiology
    • Infectious Diseases

    Background:

    • Sever's disease, or calcaneal apophysitis, is a common cause of posterior heel pain in active children, typically diagnosed via clinical exam, radiographs, and ultrasound.
    • It is generally a self-limiting condition managed conservatively, with symptoms usually resolving with rest and supportive care.

    Observation:

    • A 9-year-old boy presented with persistent heel pain, initially diagnosed with bilateral Sever's disease.
    • Magnetic resonance imaging (MRI) revealed an osteolytic lesion in the calcaneus, with surrounding edema and contrast enhancement, raising suspicion for osteomyelitis.
    • This presentation is unusual as osteomyelitis is not a typical complication of Sever's disease.

    Findings:

    • The patient received six weeks of parenteral antibiotic therapy, leading to clinical improvement.

    Related Experiment Videos

  • Follow-up MRI demonstrated significant regression of the osteolytic lesion, with replacement by granulation tissue and new bone formation.
  • This case highlights a previously unreported complication of Sever's disease: secondary calcaneal osteomyelitis.
  • Implications:

    • Atypical or persistent cases of Sever's disease warrant advanced imaging, such as MRI, to exclude other pathologies like osteomyelitis.
    • Prompt diagnosis and appropriate antibiotic treatment are essential for managing this rare complication.
    • This case expands the differential diagnosis for pediatric heel pain and emphasizes the role of MRI in complex cases.