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Building capacity for rigorous controlled trials in autism: the importance of measuring treatment adherence

H McConachie1, S Fletcher-Watson,

  • 1Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.

Child: Care, Health and Development
|August 29, 2014
PubMed

Insights

Measuring parent adherence in early autism intervention is crucial but often overlooked. Few studies assess how parents implement strategies, hindering large-scale European trials for children with autism.

Area of Science:

  • Child Psychology
  • Developmental Neuroscience
  • Clinical Psychology

Background:

  • European research groups are collaborating on early intervention for preschool children with autism.
  • Developing multi-site randomized controlled trials (RCTs) requires robust methods for evaluating parent-mediated therapies.

Purpose of the Study:

  • To assess current practices in measuring parent adherence in early autism intervention studies.
  • To identify challenges and needs for future pan-European early intervention RCTs.

Main Methods:

  • Systematic review of parent-mediated early intervention studies in autism.
  • Analysis of data from a Cochrane Collaboration review and a mapping of European studies (post-2002).
  • Focus on methods used to describe and assess parent adherence to therapeutic strategies.

Main Results:

  • Less than half of the 32 reviewed studies included any measure of parent adherence.
  • Only seven studies utilized a direct assessment method for parent adherence.
  • Significant challenges exist for pan-European studies, including outcome selection, tool translation, and assessor training.

Conclusions:

  • Current measurement of parent adherence in early autism intervention is insufficient.
  • Further research is needed on parent-child interaction and adherence measurement for effective early intervention.
  • Standardized methods are essential for successful multi-site European trials in autism intervention.

Keywords:
adherenceautismearly interventionparent-child interaction

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