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Combined T2 -preparation and two-dimensional pencil-beam inner volume selection
Andrew J Coristine1,2, Ruud B van Heeswijk1,2, Matthias Stuber1,2
1Department of Radiology, University Hospital (CHUV) / University of Lausanne (UNIL), Lausanne, VD, Switzerland.
Magnetic Resonance in Medicine
|August 29, 2014
Summary
The novel two-dimensional (2D) T2 -preparation technique significantly enhances coronary magnetic resonance angiography (MRA) vessel sharpness and reduces motion artifacts. This method preserves signal-to-noise and contrast-to-noise ratios for improved cardiac imaging.
Area of Science:
- Cardiovascular Imaging
- Magnetic Resonance Imaging
- Medical Technology
Background:
- Coronary magnetic resonance angiography (MRA) is crucial for diagnosing heart conditions.
- Improving image quality, particularly vessel sharpness and reducing motion artifacts, remains a key challenge in MRA.
- Existing T2-preparation methods have limitations in optimizing these parameters.
Purpose of the Study:
- To introduce and evaluate a novel "2D-T2 -Prep" technique for coronary MRA.
- To enhance vessel sharpness and reduce respiratory motion artifacts in coronary MRA.
- To assess the impact of 2D-T2 -Prep on signal-to-noise (SNR) and contrast-to-noise (CNR) ratios.
Main Methods:
- Modified an adiabatic T2 -preparation module by incorporating a two-dimensional (2D) spatially selective radiofrequency (RF) pulse.
- The technique excites a pencil-beam volume, with a nonselective final RF pulse restoring the T2 -prepared state within this volume.
- Evaluated through numerical simulations, phantom studies, and in vivo coronary MRA, including reduced field-of-view (rFoV) imaging.
Main Results:
- In vivo, 2D-T2 -Prep significantly improved vessel sharpness compared to conventional T2 -Prep.
- No adverse effects on SNR or CNR were observed with 2D-T2 -Prep.
- Respiratory motion artifacts were reduced, and a 60% scan time reduction was achieved with rFoV imaging, albeit with decreased SNR and CNR.
Conclusions:
- The 2D-T2 -Prep technique offers superior vessel sharpness and reduced respiratory ghosting in coronary MRA compared to conventional T2 -Prep.
- This method effectively preserves SNR and CNR, crucial for diagnostic accuracy.
- 2D-T2 -Prep also enables accelerated data acquisition through rFoV imaging.
