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Vesicoureteric reflux in children

Kjell Tullus1

  • 1Department of Nephrology, Great Ormond Street Hospital for Children, London, UK.

Lancet (London, England)
|August 29, 2014
PubMed

Insights

Vesicoureteric reflux (VUR), the backward flow of urine to the kidneys, affects many infants. This seminar reviews current management strategies for pediatric VUR, emphasizing updated guidelines and controversial recommendations.

Area of Science:

  • Pediatric Nephrology
  • Urology

Background:

  • Vesicoureteric reflux (VUR) involves urine flowing backward from the bladder to the ureters and kidneys, primarily impacting infants.
  • Severe VUR can lead to ureteral and renal pelvis dilation.
  • Recent studies indicate a higher prevalence of VUR in children (25-40%) than previously believed.

Purpose of the Study:

  • To present data on the management of pediatric vesicoureteric reflux.
  • To offer guidance on navigating current, often controversial, recommendations for VUR management in children.

Main Methods:

  • Review of current literature and clinical data on pediatric vesicoureteric reflux.
  • Analysis of existing guidelines regarding VUR investigation and treatment.

Main Results:

  • Traditional views on VUR prevalence may be underestimated; current estimates suggest 25-40% of affected children.
  • Guidelines recommend reducing investigations for VUR after febrile urinary tract infections.
  • Prophylactic antibiotics and surgery are advised against for non-severe pediatric VUR cases.

Conclusions:

  • Current management guidelines for pediatric VUR are debated.
  • A critical review of VUR management strategies is necessary for optimal patient care.
  • This seminar aims to provide clarity and suggestions for managing children with VUR.

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