Microdissection approaches in tuberculosis research
Teresa A Hudock1, Andrew A Lackner, Deepak Kaushal
1Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA, USA; Veterinary Pathology (T32) Training Program, Tulane National Primate Research Center, Covington, LA, USA.
Abstract:
Mycobacterium tuberculosis, a globally significant pathogen, results in active or latent tuberculosis. The granuloma is the characteristic lesion that offers insight into host-pathogen interactions in these distinct states. Microdissection provides a way to isolate and consequently investigate specific tissue sections. We review various techniques available and in use.
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