Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The localization-related epilepsies: some problems with subclassification.

K Watanabe1

  • 1Department of Pediatrics, Nagoya University School of Medicine, Japan.

The Japanese Journal of Psychiatry and Neurology
|September 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of drugs acting on Cl(-)-HCO3- and Na(+)-H+ exchangers on acid secretion in the rat gastric mucosa sheet preparation.

European journal of pharmacology·1992
Same author

Plasminogen activator in periodontal health and disease.

Annals of the New York Academy of Sciences·1992
Same author

Abnormal continuous flow in giant intracranial aneurysm detected by transcranial Doppler sonography--case report.

Neurologia medico-chirurgica·1992
Same author

Production and characterization of two monoclonal antibodies to human glutathione peroxidase.

Hybridoma·1992
Same author

[Distribution of Clostridium botulinum and Clostridium tetani in Okinawa Prefecture].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1992
Same author

[Acute toxicity study of 6-amidino-2-naphthyl 4-[(4,5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187) in mice, rats and dogs.

The Journal of toxicological sciences·1992

Childhood epilepsies present nosological challenges due to evolving seizure foci. Some epilepsy types can transform into others, highlighting the dynamic nature of pediatric epilepsy syndromes.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Epileptology

Background:

  • Childhood epilepsies exhibit complex nosological issues, particularly the age-related evolution of epileptic foci.
  • Understanding these transformations is crucial for accurate diagnosis and management of pediatric epilepsy syndromes.

Purpose of the Study:

  • To explore the dynamic changes in epileptic foci across different childhood epilepsy syndromes.
  • To elucidate the evolutionary relationships between various focal and generalized epilepsy types in children.

Main Methods:

  • Review of clinical and electroencephalographic (EEG) data from pediatric epilepsy cohorts.
  • Analysis of seizure semiology and EEG patterns to identify evolutionary changes in epilepsy types.
  • Classification of epilepsy syndromes based on seizure types and EEG characteristics.

Related Experiment Videos

Main Results:

  • Benign childhood epilepsy with centro-temporal spikes can evolve into childhood epilepsy with occipital paroxysms, and vice versa.
  • West syndrome, typically generalized, may present with or evolve from partial seizures.
  • Epilepsies with mixed focal and generalized seizures show varying links to generalized (e.g., severe myoclonic epilepsy in infancy) or focal (e.g., epilepsy with continuous spike-waves during slow sleep) epilepsy.

Conclusions:

  • The nosology of childhood epilepsies is complicated by the age-dependent evolution and interconversion of epileptic foci.
  • Partial epilepsies can transiently develop nonconvulsive generalized seizures, and even localization-related epilepsies may exhibit generalized discharges.
  • Recognizing these dynamic changes is essential for refining epilepsy classification and treatment strategies in pediatric populations.