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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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The calcineurin inhibitor tacrolimus reduces proteinuria in membranous nephropathy accompanied by a decrease in

Lei Peng1, Jing Ma2, Rui Cui2

  • 1Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China; Department of Nephrology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, People's Republic of China.

Plos One
|August 29, 2014
PubMed
Summary

Tacrolimus reduces proteinuria in membranous nephropathy by lowering angiopoietin-like-4 (Angptl4) in podocytes, promoting kidney repair. This study reveals a key mechanism for tacrolimus in treating this kidney disease.

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