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Updated: Apr 25, 2026

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Does pterygopalatine canal injection with local anaesthetic and adrenaline decrease bleeding during functional

C J Valdes1, Y Al Badaai2, M Bogado1

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The Journal of Laryngology and Otology
|August 29, 2014
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Summary
This summary is machine-generated.

Pterygopalatine fossa injection did not reduce surgical bleeding or operative time in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery. This intervention showed no significant impact on blood loss or procedure duration.

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Area of Science:

  • Otolaryngology
  • Surgical Innovation
  • Anesthesia

Background:

  • Chronic rhinosinusitis (CRS) management often involves functional endoscopic sinus surgery (FESS).
  • Optimizing surgical conditions, such as minimizing bleeding and procedure time, is crucial for effective FESS.
  • Pterygopalatine fossa (PPF) injection is a potential method to improve surgical field visualization and efficiency.

Purpose of the Study:

  • To evaluate the efficacy of pterygopalatine fossa injection with xylocaine and adrenaline.
  • To assess its impact on intraoperative surgical field bleeding and overall blood loss during FESS for CRS.
  • To determine if PPF injection influences the duration of the surgical procedure.

Main Methods:

  • Prospective, single-blinded, controlled trial involving 45 CRS patients with symmetrical disease.
  • Unilateral PPF injection with 1% xylocaine and 1:100,000 adrenaline, with the contralateral side as control.
  • Surgeon-assessed surgical field grading, recorded blood loss, vital signs, and procedure duration.

Main Results:

  • No statistically significant difference in surgical field grade between injected and non-injected sides (p=0.161).
  • No significant differences observed in intraoperative blood loss between the two sides.
  • The duration of the functional endoscopic sinus surgery was not affected by the PPF injection.

Conclusions:

  • Pterygopalatine fossa injection prior to FESS does not effectively decrease intraoperative bleeding.
  • This technique did not lead to reduced blood loss or shorter surgical duration in CRS patients.
  • The study suggests PPF injection is not beneficial for improving surgical field conditions in FESS for CRS.