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Updated: Apr 25, 2026

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
Published on: March 18, 2017
Improved determination of G using two methods
Terry Quinn1, Harold Parks1, Clive Speake2
1BIPM, Pavillon de Breteuil, 92312 Sèvres cedex, France.
Abstract:
This Letter describes new work on the determination of the Newtonian constant of gravitation, G, carried out at the BIPM since publication of the first results in 2001. The apparatus has been completely rebuilt and extensive tests carried out on the key parameters needed to produce a new value for G. The basic principles of the experiment remain the same, namely a torsion balance suspended from a wide, thin Cu-Be strip with two modes of operation, free deflection (Cavendish) and electrostatic servo control. The result from the new work is: G=6.67545(18)×10(-11) m3 kg(-1) s(-2) with a standard uncertainty of 27 ppm. This is 21 ppm below our 2001 result but 241 ppm above The CODATA 2010 value, which has an assigned uncertainty of 120 ppm. This confirms the discrepancy of our results with the CODATA value and highlights the wide divergence that now exists in recent values of G. The many changes made to the apparatus lead to the formal correlation between our two results being close to zero. Being statistically independent and statistically consistent, the two results taken together provide a unique contribution to determinations of G.
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