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Updated: Apr 25, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
[Peritoneal gliomatosis]
Angela Sánchez-Cifuentes1, Francisco Miguel Gonzalez-Valverde2, María Vicente-Ruiz2
1Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario Reina Sofía, Murcia, Spain. angelasanchez.cif@gmail.com.
Background:
Peritoneal gliomatosis is characterized by the presence of miliary implants of mature glia on the peritoneum of patients with ovarian teratomas, usually immature.
Clinical Case:
We report the case of a woman operated on 5 years earlier due to a right mature ovarian teratoma. When she was operated on due to left ovarian tumor she presented a miliary glial dissemination in omentum and peritoneum.
Conclusion:
The association of peritoneal gliomatosis ovarian teratomas is rare. Although the primary treatment and patient monitoring is focused on the teratoma, control should be maintained of peritoneal implants because of the possibility of malignancy. We believe it would be beneficial to establish a protocol for monitoring these lesions.

