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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

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[Masked hypertension]

Hiroaki Matsuoka

    Nihon Rinsho. Japanese Journal of Clinical Medicine
    |August 30, 2014
    PubMed

    Insights

    Masked hypertension, normal in-office blood pressure but high out-of-office readings, elevates cardiovascular risk. Lifestyle changes and precise blood pressure management are crucial for treatment.

    Area of Science:

    • Cardiology
    • Hypertension Research
    • Preventive Medicine

    Context:

    • Masked hypertension is characterized by normal office blood pressure readings despite elevated out-of-office levels.
    • Out-of-office blood pressure monitoring, via ambulatory blood pressure monitoring (ABPM) or home blood pressure measurements (HBPM), is key to diagnosis.
    • While HBPM is common in Japan due to simplicity, ABPM is vital for assessing nocturnal blood pressure patterns.

    Purpose:

    • To highlight the diagnostic methods and clinical significance of masked hypertension.
    • To identify contributing factors and associated risks of masked hypertension.
    • To outline essential treatment strategies for masked hypertension.

    Summary:

    • Patients with masked hypertension exhibit normal clinic blood pressure but elevated readings during ambulatory blood pressure monitoring (ABPM) or home blood pressure measurements (HBPM).
    • This condition carries a cardiovascular morbidity risk comparable to established hypertension.
    • Contributing factors include lifestyle (smoking, alcohol), blood pressure variability (e.g., morning surge, non-dipper patterns), and inadequate hypertension treatment.

    Impact:

    • Masked hypertension poses a significant, often undetected, cardiovascular risk.
    • Early identification and management are essential to mitigate long-term cardiovascular complications.
    • Effective treatment involves lifestyle modifications, rigorous blood pressure control, and addressing underlying conditions.

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