Pathogenesis of Helicobacter pylori infection
Marina de Bernard1, Christine Josenhans
1Department of Biology, University of Padova, Padova, Italy.
Abstract:
Helicobacter pylori relies on multiple colonization and virulence factors to persist in the human stomach for life. In addition, these factors can be modulated and vary to suit the ever-changing environment within the host individual. This article outlines the novel developments in this field of research during the past year, highlighting the cag pathogenicity island, VacA, γ-glutamyl-transpeptidase as well as including recent advances in protein structure, bacteria-host interaction, and the role of stomach microbiota.
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