99mTc-HMPAO-labeled WBC scan for the diagnosis of chronic recurrent multifocal osteomyelitis
Tyler A Dailey1, Michael D Berven2, Penny J Vroman2
1Department of Radiology, San Antonio Military Medical Center, Fort Sam Houston, Texas tyler.a.dailey2.mil@mail.mil.
Abstract:
The goal of this teaching case study is to demonstrate the novel use of (99m)Tc-HMPAO-labeled white blood cells (WBCs) in diagnosing chronic recurrent multifocal osteomyelitis (CRMO). (99m)Tc-HMPAO-labeled white blood cells were utilized to diagnose CRMO. Classically, CRMO is evaluated scintigraphically using (99m)Tc-methylene diphosphonate/hydroxymethylene diphosphonate. (99m)Tc-HMPAO-labeled WBCs were chosen over (111)In-labeled WBCs because of the former's improved imaging characteristics and decreased radiation dose. (99m)Tc-HMPAO-labeled WBCs were successful in diagnosing CRMO. (99m)Tc-HMPAO-labeled WBC scanning is specific for the diagnosis of CRMO.
