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Hyperuricemia: a possible cause of hemospermia
Adel Kurkar1, Ahmad A Elderwy1, Sara M Awad2
1Department of Urology, Assiut University Hospitals, Assiut University, Asyut, Egypt.
Urology
|August 30, 2014
Summary
Hyperuricemia is identified as a new potential cause of hemospermia. Treatment for hyperuricemia led to complete resolution of hemospermia in all patients studied.
Area of Science:
- Urology
- Nephrology
- Andrology
Background:
- Hemospermia, or blood in semen, can be caused by various conditions.
- Hyperuricemia, elevated serum uric acid levels, has not been widely recognized as a cause of hemospermia.
Purpose of the Study:
- To investigate the relationship between hemospermia and hyperuricemia.
- To compare clinical characteristics and outcomes of hemospermia patients with and without hyperuricemia.
Main Methods:
- A prospective study of 143 hemospermia patients from July 2005 to July 2012.
- 43 patients with idiopathic hemospermia were identified; 22 had hyperuricemia.
- Comparison of clinical data and treatment outcomes between hyperuricemic and idiopathic hemospermia groups.
Main Results:
- Hyperuricemia was the second most common cause of hemospermia (15.4%) in the study cohort.
- Hyperuricemic patients were younger, experienced more painful ejaculation, and had higher serum uric acid levels.
- Complete resolution of hemospermia occurred in 100% of hyperuricemic patients versus 25% of idiopathic cases within 2 months.
Conclusions:
- Hyperuricemia is a newly identified probable cause of hemospermia.
- Treatment targeting hyperuricemia appears effective in resolving hemospermia.
- Further randomized controlled trials are needed to confirm these findings.
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