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Published on: June 8, 2016
Synthesis and self-assembly behavior of a biodegradable and sustainable soybean oil-based copolymer nanomicelle
Lixia Bao1, Longchun Bian2, Mimi Zhao2
1State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China ; School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
Abstract:
Herein, we report a novel amphiphilic biodegradable and sustainable soybean oil-based copolymer (SBC) prepared by grafting hydrophilic and biocompatible hydroxyethyl acrylate (HEA) polymeric segments onto the natural hydrophobic soybean oil chains. FTIR, H(1)-NMR, and GPC measurements have been used to investigate the molecular structure of the obtained SBC macromolecules. Self-assembly behaviors of the prepared SBC in aqueous solution have also been extensively evaluated by fluorescence spectroscopy and transmission electron microscopy. The prepared SBC nanocarrier with the size range of 40 to 80 nm has a potential application in the biomedical field.
