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Impaired Object Handling during Bimanual Task Performance in Multiple Sclerosis.

Stacey L Gorniak1, Matthew Plow2, Corey McDaniel2

  • 1Department of Health and Human Performance, University of Houston, 3855 Holman Street, Garrison 104U, Houston, TX 77204, USA ; Centers for Neuromotor and Biomechanics Research and Neuro-Engineering and Cognitive Science, University of Houston, Houston, TX 77204, USA.

Multiple Sclerosis International
|August 30, 2014
PubMed
Summary
This summary is machine-generated.

Persons with relapsing-remitting multiple sclerosis (PwMS) show impaired motor control, including increased grip force and timing deficits. Objective measurements correlate with their perceived disability.

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Area of Science:

  • Neurology
  • Biomechanics
  • Rehabilitation Science

Background:

  • Relapsing-remitting multiple sclerosis (MS) significantly impacts daily activities, particularly those requiring fine motor control and manual dexterity.
  • Understanding the specific kinetic alterations in upper-extremity function is crucial for developing targeted interventions.
  • Previous research has often relied on subjective assessments, necessitating objective, quantitative measures.

Purpose of the Study:

  • To investigate the kinetic features of manual dexterity and fine motor control in persons with relapsing-remitting multiple sclerosis (PwMS) during a functional task.
  • To compare motor control parameters, including grip force, kinetic timing, and grip-load coupling, between PwMS and healthy controls.
  • To explore the relationship between objective motor performance measures and self-reported disability in PwMS.

Main Methods:

  • A novel two-transducer system was employed to measure time and grip-load forces during a bimanual task simulating jar opening/closing.
  • Thirty persons with relapsing-remitting multiple sclerosis (PwMS) and healthy controls (young and older adults) participated.
  • Kinetic variables such as task completion time, grip force magnitude, and grip-load coupling indices were analyzed.

Main Results:

  • Persons with relapsing-remitting multiple sclerosis (PwMS) demonstrated significantly increased grip force production compared to controls.
  • Deteriorations in kinetic timing indices were observed in PwMS, indicating slower and less precise movements.
  • Abnormal grip-load coupling patterns were exhibited by PwMS, differing from the preserved coupling in healthy participants.
  • A significant correlation was found between task completion time and self-reported disability scores.

Conclusions:

  • Persons with relapsing-remitting multiple sclerosis (PwMS) exhibit distinct kinetic alterations in manual dexterity, including hyperactive grip force and impaired timing.
  • Grip-load coupling is disrupted in PwMS, suggesting a potential compensatory strategy or underlying motor control deficit.
  • Objective kinetic measurements provide valuable insights into the functional limitations experienced by PwMS and correlate with their perceived disability.