Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

2.0K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
2.0K
Traumatic Memory01:20

Traumatic Memory

756
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
756
Long-Term Memory01:18

Long-Term Memory

918
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
918
Interference and Decay01:16

Interference and Decay

605
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
605
Storage01:23

Storage

502
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
502
Implicit Memories01:24

Implicit Memories

629
Implicit memories, also known as non-declarative memories, are long-term memories that function outside of conscious awareness. These memories influence behavior and skills without explicit knowledge. This type of memory is evident in tasks like playing tennis, snowboarding, and texting. Implicit memory has three subsystems: procedural memory, conditioning, and priming. This type of memory is essential in various activities, from everyday tasks to specialized skills.
One key aspect of implicit...
629

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Enhancing companion animal welfare through advanced behavioral management strategies.

Frontiers in behavioral neuroscience·2026
Same author

Obesogenic diet impairs memory consolidation via the hippocampal endocannabinoid system.

Current biology : CB·2025
Same author

Evaluation of the performance of topical products containing Ophytrium and chlorhexidine digluconate in cats with local cutaneous bacterial and/or <i>Malassezia pachydermatis</i> overgrowth.

Journal of feline medicine and surgery·2025
Same author

Efficacy of a pheromone-impregnated collar in controlling feline problem behaviors, and an assessment of adverse events associated with collar use.

Frontiers in veterinary science·2025
Same author

Performance of applications of Ophytrium-containing mousse with or without shampoo in cats with pruritic and irritated skin: a multicentre prospective field trial.

Journal of feline medicine and surgery·2024
Same author

Evaluating undesired scratching in domestic cats: a multifactorial approach to understand risk factors.

Frontiers in veterinary science·2024

Related Experiment Video

Updated: Apr 25, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.8K

Characterization of spatial memory reconsolidation.

Xavier De Jaeger1, Julie Courtey1, Maïna Brus1

  • 1Université de Toulouse, Université Paul Sabatier, 31062 Toulouse Cedex 9, France Centre de Recherches sur la Cognition Animale, CNRS UMR 5169, 31062 Toulouse Cedex 9, France.

Learning & Memory (Cold Spring Harbor, N.Y.)
|August 30, 2014
PubMed
Summary

Memory reconsolidation in mice depends on memory age and strength. Protein synthesis is required for older, weaker memories but not recent, strong ones, influencing brain region activation.

More Related Videos

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
11:17

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

33.1K
Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic &#946;-Blocker
08:32

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Published on: December 18, 2014

25.3K

Related Experiment Videos

Last Updated: Apr 25, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.8K
Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
11:17

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

33.1K
Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic &#946;-Blocker
08:32

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Published on: December 18, 2014

25.3K

Area of Science:

  • Neuroscience
  • Memory research
  • Animal behavior

Background:

  • Memory reconsolidation is crucial for stabilizing reactivated memories.
  • The influence of memory characteristics on reconsolidation remains incompletely understood.
  • Previous research suggests experimental parameters can affect reconsolidation.

Purpose of the Study:

  • To investigate how memory age, strength, and update influence reconsolidation in mice.
  • To determine the necessity of protein synthesis for reconsolidation under different memory conditions.
  • To examine the role of specific brain regions in the reconsolidation of reactivated memories.

Main Methods:

  • Mice were trained on spatial memory tasks with varying acquisition levels.
  • Protein synthesis inhibition was used to assess its necessity for reconsolidation.
  • Electrophysiological recordings were employed to monitor neural activity in the hippocampal CA3 and anterior cingulate cortex.

Main Results:

  • Protein synthesis is essential for reconsolidation of partially acquired and old memories in the hippocampal CA3, but not for strongly acquired, recent memories.
  • Updating a stable memory trace also necessitates reconsolidation in the hippocampal CA3.
  • Reactivation of strongly acquired memories triggers anterior cingulate cortex activation within 24 hours.

Conclusions:

  • Memory reconsolidation is a dynamic process influenced by memory age and strength.
  • The necessity of protein synthesis for reconsolidation varies with memory characteristics.
  • Specific brain circuits, including the hippocampal CA3 and anterior cingulate cortex, are differentially involved in memory reconsolidation.