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Related Experiment Video

Updated: Apr 25, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Asbestos-related diffuse pleural thickening.

Nobukazu Fujimoto¹, Katsuya Kato, Ikuji Usami

¹Department of Medical Oncology, Okayama Rosai Hospital, Okayama, Japan.

Respiration; International Review of Thoracic Diseases

|August 30, 2014

Summary

Asbestos-related diffuse pleural thickening (DPT) develops years after exposure, significantly impairing respiratory function. Radiological assessment using chest CT and X-ray is crucial for evaluating DPT extent and its impact on lung health.

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Published on: December 21, 2019

Area of Science:

Pulmonary Medicine
Occupational Health
Radiology

Background:

Clinical features of asbestos-related diffuse pleural thickening (DPT) are not well understood.
DPT is a significant consequence of asbestos exposure.

Purpose of the Study:

To investigate the relationship between radiological findings of DPT and respiratory function.
To elucidate the clinical presentation of asbestos-induced DPT.

Main Methods:

Retrospective analysis of medical data from 106 DPT patients (2005-2010).
Inclusion of occupational history, symptoms, smoking status, and respiratory function tests.
Radiological assessment using chest X-ray and computed tomography (CT).

Main Results:

DPT diagnosis occurred at a median age of 69 after a median exposure duration of 25 years and a median latency of 46 years.
Increased pleural thickness and extension on CT scans correlated negatively with percent vital capacity (%VC).
Costophrenic angle involvement also showed a negative correlation with %VC.

Conclusions:

Asbestos-related DPT has a long latency period and leads to substantial respiratory impairment.
Chest CT is recommended for assessing the extent of pleural thickening.
Chest X-ray is valuable for evaluating costophrenic angle involvement in DPT.