Polyelectrolyte coatings prevent interferences from charged nanoparticles in SPME speciation analysis

Area of Science:

• Analytical Chemistry
• Materials Science

Background:

• Solid phase microextraction (SPME) is susceptible to interference from charged particles in sample matrices.
• Protecting the extraction fiber is crucial for reproducible and accurate analyte quantification.

Purpose of the Study:

• To develop a new method for protecting SPME fibers from interfering charged particles.
• To enhance the extraction efficiency and selectivity for triclosan (TCS) in complex samples.

Main Methods:

• Coating commercial poly(dimethylsiloxane) (PDMS) fibers with a polyelectrolyte layer (poly(diallyldimethylammonium chloride) and poly(sodium 4-styrenesulfonate)).
• Utilizing the modified fiber for the extraction of triclosan in the presence of oxidic nanoparticles.
• Performing dynamic speciation analysis of the nanoparticulate target analyte complex.

Main Results:

• The polyelectrolyte coating effectively prevented partitioning and aggregation of oxidic nanoparticles onto the PDMS phase.
• The modified fiber demonstrated reproducible, convenient, and fast extraction of triclosan.
• The method enabled selective extraction of the free form of triclosan, allowing for dynamic speciation analysis.

Conclusions:

• The polyelectrolyte-modified SPME fiber offers robust protection against interfering charged particles.
• This approach significantly improves the analytical performance for triclosan analysis in nanoparticle-containing samples.
• The developed technique facilitates dynamic speciation analysis of complex nanoparticulate analyte systems.