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Updated: Apr 25, 2026
Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury
Published on: December 17, 2014
Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury
Virginie Neirinckx1, Bernard Rogister, Rachelle Franzen
1Groupe Interdisciplinaire de Génoprotéomique appliquée (GIGA), Neurosciences Unit, University of Liège, Avenue de l'Hopital 1 - B36, Liège, 4000, Belgium, Virginie.Neirinckx@ulg.ac.be.
Abstract:
Spinal cord injured experimental animals are widely used for studying pathophysiological processes after central nervous system acute traumatic lesion and elaborating therapeutic solutions, some of them based on stem cell transplantation. Here, we describe a protocol of spinal cord contusion in C57BL/6J mice, directly followed by bone marrow stromal stem cells transplantation. This model allows for the characterization of neuroprotective and neurorestorative abilities of these stem cells in a context of spinal cord trauma.
