Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cleavage and Blastulation01:33

Cleavage and Blastulation

42.2K
After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
42.2K
Diversity of Protists I01:15

Diversity of Protists I

2.3K
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
2.3K
Diversity of Protists IV01:27

Diversity of Protists IV

2.1K
Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
2.1K
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

6.2K
The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
6.2K
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

5.8K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
5.8K
Genetic Variation01:25

Genetic Variation

1.6K
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reassessing Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: A Comparative Study of Diagnostic Guidelines and Their Clinical Relevance.

Journal of gastroenterology and hepatology·2026
Same author

Differential Metabolic and Transcriptional Responses of PBMCs to Blastocystis sp. Subtypes in Chemotherapy-Treated Colorectal Cancer Patients.

Acta parasitologica·2026
Same author

Machine Learning Models Using Hospital Admission Characteristics Do Not Optimally Predict Nosocomial Infection Development in a Global Cirrhosis Cohort.

The American journal of gastroenterology·2026
Same author

Frequency, Predictive Factors, and Burden of Gastrointestinal Symptoms in Patients With Type 2 Diabetes.

JGH open : an open access journal of gastroenterology and hepatology·2026
Same author

Symptom Patterns Outside the Rome IV Consensus in Eastern and Western Patients With a Disorder of Gut-Brain Interaction.

The American journal of gastroenterology·2026
Same author

Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations.

Journal of gastroenterology and hepatology·2026

Related Experiment Video

Updated: Apr 25, 2026

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
12:09

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

Published on: August 10, 2022

7.2K

Phenotypic variation in Blastocystis sp. ST3.

Nanthiney Devi Ragavan, Suresh Kumar Govind1, Tan Tian Chye

  • 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. suresh@um.edu.my.

Parasites & Vectors
|September 2, 2014
PubMed
Summary
This summary is machine-generated.

Blastocystis subtype 3 shows distinct phenotypic variations based on host gut conditions, adapting its growth and surface characteristics. This study reveals how the gut environment influences Blastocystis morphology and behavior.

More Related Videos

Human Blastocyst Biopsy and Vitrification
10:59

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

22.9K
Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps
08:28

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps

Published on: February 28, 2019

8.4K

Related Experiment Videos

Last Updated: Apr 25, 2026

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
12:09

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

Published on: August 10, 2022

7.2K
Human Blastocyst Biopsy and Vitrification
10:59

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

22.9K
Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps
08:28

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps

Published on: February 28, 2019

8.4K

Area of Science:

  • Microbiology
  • Parasitology
  • Gastroenterology

Background:

  • Blastocystis is a common human intestinal protozoan with debated pathogenicity.
  • Gut conditions (flora, pH, osmotic pressure) may influence Blastocystis pathogenicity.
  • Phenotypic characteristics of Blastocystis ST3 isolates from different host groups were previously uninvestigated.

Purpose of the Study:

  • To investigate phenotypic characteristics of Blastocystis sp. ST3.
  • To compare Blastocystis ST3 isolates from asymptomatic, symptomatic, and Irritable Bowel Syndrome (IBS) patients.

Main Methods:

  • Isolated Blastocystis ST3 from 12 individuals: 4 IBS patients, 4 symptomatic patients, and 4 asymptomatic individuals.
  • Analyzed growth profiles, parasite diameter, generation time, aggregation, and surface properties using microscopy and lectin binding.

Main Results:

  • All isolates were Blastocystis ST3; asymptomatic isolates showed highest peak growth, while symptomatic isolates had the fastest generation time.
  • IBS isolates exhibited larger diameters, increased surface folding, thicker surface coats, and greater Concanavalin A binding compared to symptomatic and asymptomatic isolates.
  • Parasites from IBS isolates showed significant clumping, unlike symptomatic and asymptomatic isolates.

Conclusions:

  • This is the first study demonstrating phenotypic variation within Blastocystis ST3.
  • The gut environment appears to facilitate adaptation and induce phenotypic differences in Blastocystis, potentially for survival.
  • Findings suggest host gut conditions significantly influence Blastocystis characteristics.