Serum brain-derived neurotrophic factor (BDNF) and its association with remission status in Chinese patients with
Vidhya Renjan1, Milawaty Nurjono1, Jimmy Lee2
1Research Division, Institute of Mental Health, Singapore.
Abstract:
The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to examine if serum BDNF level is associated with remission status in a sample of Chinese patients with schizophrenia. This study did not find a significant relationship between serum BDNF and remission in patients with schizophrenia. Identification of a suitable biomarker for diagnosis, management, and prognostic outcome is crucial and warrants further study.


